PHChen Laboratory

Membrane vesicle trafficking Lab, Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University


Lakoduk AM, Roudot P, Mettlen M,Grossman HM, Schmid SL and Chen PH (2019). Mutant p53 amplifies a dynamin-1/APPL1 endosome feedback loop that regulates recycling and migration. J Cell Biol. doi: 10.1083/jcb.201810183

Mettlen M, Chen PH, Srinivasan S, Danuser G and Schmid SL (2018). Regulation of clathrin mediated endocytosis. Annual Review of Biochemistry.87: 871-896 doi: 10.1146/annurev-biochem-062917-012644.

Srinivasan S, Burkhardt C, Bhave M, Chen Z, Chen PH, Wang X, Danuser G and Schmid SL (2018).A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells. PLoS Biol.16(4): e2005377 doi: 10.1371/journal.pbio.2005377

Chen PH* , Yao H and Huang LJ (2017). Cytokine receptor endocytosis: new kinase activity-dependent and –independent roles of PI3K. Frontiers in Endocrinology. 8: 78. (*first author, Mini-review) doi: 10.3389/fendo.2017.00078.

Chen PH* , Bendris N, Hsiao YJ, Reis CR, Mettlen M, Chen HY, Yu SL, and Schmid SL (2017).Crosstalk between CLCb/Dyn1-mediated adaptive CME and EGFR signaling increases metastasis. Dev Cell. 40:278-288.(*first and co-corresponding author) doi: 10.1016/j.devcel.2017.01.007

Reis CR, Chen PH, Bendris N, Schmid SL (2017). Death receptor endocytosis and apoptosis are regulated by dynamin-1 activation. PNAS. 114(3): 504-509 doi: 10.1073/pnas.1615072114

Bendris N, Williams KC, Reis CR, Welf ES, Chen PH, Lemmers B, Hahne M, Leong HS, Schmid SL (2016).SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of Rho GTPases. Mol. Biol. Cell .27(9): 1409-1419 doi: 10.1091/mbc.E16-02-0101

Reis CR*, Chen PH*, Srinivasan S, Aguet F, Mettlen M, and Schmid SL (2015). Crosstalk between AKT/GSK3beta signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J. 34: 2132-2146 (*co-first author) doi: 10.15252/embj.201591518

Chen PH*, Chien FC, Lee SP, Chan WE, Lin IH, Liu CS, Lee FJ, Lai JS, Chen P, Yang-Yen HF and Yen JJ. (2012).Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2. Cell Cycle11(19): 3611-3626 (*first author) doi: 10.4161/cc.21920

Kao CJ, Chiang YJ, Chen PH, Lin KR, Hwang PI, Yang-Yen HF, and Yen J JY (2008).CBAP Interacts with the Un-liganded Common beta Subunit of the GM-CSF/IL-3/IL-5 Receptor and Induces Apoptosis via Mitochondria Dysfunction. Oncogene 27(10): 1397-1403 doi: 10.1038/sj.onc.1210778

Tseng YS, Tzeng CC, Huang CY, Chen PH, Chiu AW, Hsu PY, Huang GC, Wang YC, Liu HS. (2006).Aurora-A overexpression associates with Ha-ras codon-12 mutation and blackfoot disease endemic area in bladder cancer. Cancer Lett.241(1): 93-101 doi: 10.1016/j.canlet.2005.10.014

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