Model of CLCb/Dyn1-dependent adaptive CME

Adaptive CME

References:

1. Chen PH*, Bendris N, Hsiao YJ, Reis CR, Mettlen M, Chen HY, Yu SL, and Schmid SL (2017). Crosstalk between CLCb/Dyn1-mediated adaptive CME and EGFR signaling increases metastasis. Dev Cell 40:278-288  doi: 10.1016/j.devcel.2017.01.007.

2. Schmid SL (2017). Reciprocal regulation of signaling and endocytosis: Implications for the evolving cancer cell. J Cell Biol 216:2623-2632 doi: 10.1083/jcb.201705017.